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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1981-2-19
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pubmed:abstractText |
381 sera from 101 patients suffering from Pseudomonas aeruginosa infection have been investigated for antibodies against a 'common antigen' (CA) and other antigens from P. aeruginosa by means of crossed immunoelectrophoresis with intermediate gel, using a polyspecific P. aeruginosa antigen/antibody reference system. The earliest antibody response during the P. aeruginosa infections included increased CA antibodies in only 38% of the patients examined. The peak level of the antibody response included increased CA antibodies in 71% of the patients. By means of 'absorption of antibodies in situ', it was found that the antibody response to CA was directed against both the common cross-reactive part of the CA molecule and the Pseudomonas-specific part, with individual variations. During infections caused by other bacteria containing CA, one-third of the patients developed antibodies against CA. The diagnostic implications of the results are discussed.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0304-1328
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
88
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
149-54
|
pubmed:dateRevised |
2009-6-4
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pubmed:meshHeading |
pubmed-meshheading:6778073-Antibodies, Bacterial,
pubmed-meshheading:6778073-Antibody Formation,
pubmed-meshheading:6778073-Antibody Specificity,
pubmed-meshheading:6778073-Antigens, Bacterial,
pubmed-meshheading:6778073-Cross Reactions,
pubmed-meshheading:6778073-Humans,
pubmed-meshheading:6778073-Immunoelectrophoresis, Two-Dimensional,
pubmed-meshheading:6778073-Pseudomonas Infections,
pubmed-meshheading:6778073-Pseudomonas aeruginosa
|
pubmed:year |
1980
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pubmed:articleTitle |
Antibody response in patients with Pseudomonas aeruginosa infection to a 'common antigen' from P. aeruginosa analysed by means of quantitative immunoelectrophoretic methods.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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