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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1981-2-24
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pubmed:abstractText |
N-nitroso compounds were found to be carcinogenic in 22 animals species. The organotropism of the carcinogenic action may be related to a variety of organs and organ systems. It does not only depend on the chemical structure of the molecules but also on the daily dose. It is highly probable that N-nitroso compounds also act carcinogenically in human beings. Predictions as to the organotropism of the carcinogenic action in man cannot be made. N-nitroso compounds have to be regarded as 'multipotent'.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0030-2414
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
237-42
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6777721-Animals,
pubmed-meshheading:6777721-Anura,
pubmed-meshheading:6777721-Carcinogens,
pubmed-meshheading:6777721-Cats,
pubmed-meshheading:6777721-Chickens,
pubmed-meshheading:6777721-Cricetinae,
pubmed-meshheading:6777721-Dogs,
pubmed-meshheading:6777721-Dose-Response Relationship, Drug,
pubmed-meshheading:6777721-Drug Administration Schedule,
pubmed-meshheading:6777721-Female,
pubmed-meshheading:6777721-Fishes,
pubmed-meshheading:6777721-Gerbillinae,
pubmed-meshheading:6777721-Guinea Pigs,
pubmed-meshheading:6777721-Haplorhini,
pubmed-meshheading:6777721-Hedgehogs,
pubmed-meshheading:6777721-Lethal Dose 50,
pubmed-meshheading:6777721-Maternal-Fetal Exchange,
pubmed-meshheading:6777721-Mice,
pubmed-meshheading:6777721-Neoplasms, Experimental,
pubmed-meshheading:6777721-Nitroso Compounds,
pubmed-meshheading:6777721-Organ Specificity,
pubmed-meshheading:6777721-Parakeets,
pubmed-meshheading:6777721-Pregnancy,
pubmed-meshheading:6777721-Rabbits,
pubmed-meshheading:6777721-Rats,
pubmed-meshheading:6777721-Species Specificity,
pubmed-meshheading:6777721-Structure-Activity Relationship
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pubmed:year |
1980
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pubmed:articleTitle |
Carcinogenicity of N-nitroso compounds. Species and route differences in regard to organotropism.
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pubmed:publicationType |
Journal Article,
Comparative Study
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