Linked Life Data

6776221

Source:http://linkedlifedata.com/resource/pubmed/id/6776221

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1981-1-16
pubmed:abstractText
Imaginal leg and wing discs obtained from late-third-instar Drosophila larvae were cultured in vitro in various concentrations of ecdysterone ranging from 10(-10) to 10(-5) M in order to test the effect of hormone concentration on evagination and cell differentiation. At the optimal concentration of 8 x 10(-8) M discs evaginated normally, secreted the pupal cuticle, underwent apolysis, differentiated imaginal structures and secreted the imaginal cuticle. At suboptimal concentrations (10(-8) M and less), evagination was incomplete in a variable proportion of appendages. Morphogenetic movements were limited to the earlier ones; so that appendages did not emerge from the peripodial sac. Subsequent development, whenever it occurred, took place inside the peripodial sac. This particular type of 'endoevagination' was only obtained with sub-optimal hormone concentration. At supra-optimal concentrations (10(-6) M and more), evagination was always complete but further differentiation was inhibited. These results show that endoevagination is strictly related to insufficient supply of hormone and that morphogenesis and cell differentiation in imaginal discs are two independent phenomena, which respond to different levels of hormone stimulation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0022-0752
pubmed:author
pubmed:issnType
Print
pubmed:volume
57
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
107-18
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
In vitro imaginal disc development and moulting hormone.
pubmed:publicationType
Journal Article