Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
11
|
| pubmed:dateCreated |
1981-1-16
|
| pubmed:abstractText |
A bleeding disease similar to von Willebrand's disease in man was diagnosed in a 6-month-old Chesapeake Bay Retriever with recurrent, protracted gingival hemorrhage that responded rapidly to fresh, whole blood transfusions. The dog had a prolonged bleeding time and low plasma factor VIII coagulant activity (18%). The plasma had no detectable factor VIII-related antigen or von Willebrand factor, as measured by ristocetin-cofactor and polybrene-cofactor activities. The dam of the dog had a plasma factor VIII-related antigen concentration (32%) well below the normal range. The antigen in the sire's plasma was at the low end of the normal range, as was the polybrene-cofactor of both the sire and the dam. These data suggested an inherited basis for von Willebrand's disease in this dog.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0003-1488
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
176
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1261-3
|
| pubmed:dateRevised |
2009-11-19
|
| pubmed:meshHeading | |
| pubmed:year |
1980
|
| pubmed:articleTitle |
A bleeding disease (von Willebrand's disease) in a Chesapeake Bay Retriever.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Case Reports
|