Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1977-6-30
|
pubmed:abstractText |
Having applied the picric acid-bromphenol blue (BPB) and the phosphomolybdic acid-benzidine (PMA-B) methods--the first method detecting the total histone content, the second one only free histones--we have found that cell nuclei of the rat embryos permanently contain histones, nevertheless, in such a pattern that the free histone appears only at a well-defined stage of embryogenesis. Strong PMA-B reaction is observable in the nuclei of some mesenchymal cells and in the reorganizing somites' cell nuclei of the 13-day-old embryo as well as in the hemopoietic elements of the 15- and 17-day old embryos' liver. Within nuclei of the red blood cells of the 13-day-old embryo an extremely intense reaction is seen which then disappears till the 15th day, while the BPB reaction shows a gradual intensification up to the neonatal age. The experiments support the former model of one of the authors for a histone-nonhistone control of ontogenesis.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0001-5180
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
98
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
154-61
|
pubmed:dateRevised |
2007-7-2
|
pubmed:meshHeading |
pubmed-meshheading:67741-Age Factors,
pubmed-meshheading:67741-Animals,
pubmed-meshheading:67741-Benzidines,
pubmed-meshheading:67741-Bromphenol Blue,
pubmed-meshheading:67741-Cell Differentiation,
pubmed-meshheading:67741-Cell Nucleus,
pubmed-meshheading:67741-Histones,
pubmed-meshheading:67741-Rats,
pubmed-meshheading:67741-Rats, Inbred Strains,
pubmed-meshheading:67741-Staining and Labeling
|
pubmed:year |
1977
|
pubmed:articleTitle |
Appearance of free histones within nuclei of differentiating cells in the developing rat embryo.
|
pubmed:publicationType |
Journal Article
|