Linked Life Data

6771955

Source:http://linkedlifedata.com/resource/pubmed/id/6771955

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1980-9-23
pubmed:abstractText
Sera of 41 splenectomized subjects were tested for presence of autoantibodies by the indirect immunofluorescent method. 11 of them (26%) revealed the presence of one or more types of autoantibodies. Antiheart antibodies were the most common type (9 subjects). The incidence of antibodies was higher in the subjects splenectomized for trauma than in those who underwent elective splenectomy (39 and 25%, respectively). There was no significant difference between the subjects with positive and negative results with respect to mean age at examination, but the positive results tend to occur more frequently in those who underwent splenectomy at younger age. None of the subjects with any type of antibodies suffered from autoimmune disease. Although it is still impossible to evaluate the clinical importance of these findings, they suggest that splenectomy may disturb the regulatory processes in the immune system. We postulate that this is due to the reduction of the number of suppressor T cells for which the spleen is a major pool.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-5792
pubmed:author
pubmed:issnType
Print
pubmed:volume
63
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
230-3
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Autoimmune antibodies after splenectomy.
pubmed:publicationType
Journal Article