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rdf:type |
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|
lifeskim:mentions |
|
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pubmed:issue |
2
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pubmed:dateCreated |
1980-9-26
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|
pubmed:abstractText |
The effects of three formamidine pesticide or pesticide metabolites on calcium flux in the rabbit aorta were examined. U-40481 reduced the rate of both 45Ca uptake and norepinephrine (NE)-stimulated 45Ca uptake into deadventitiated rabbit aorta strips and reduced NE-stimulated efflux from 45Ca-loaded, superfused aorta strips (p less than 0.1). Neither demethylchlordimeform nor formetanate altered either 45Ca-uptake or NE-enhanced 45Ca flux. The action of U-40481 on unstimulated 45Ca uptake may result from uncoupling oxidative phosphorylation, and reduction in NE-induced 45Ca-flux may result from antagonism at NE receptors.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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|
pubmed:month |
May
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|
pubmed:issn |
0034-5164
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
215-28
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6771843-Amidines,
pubmed-meshheading:6771843-Animals,
pubmed-meshheading:6771843-Aorta,
pubmed-meshheading:6771843-Calcium,
pubmed-meshheading:6771843-Calcium Radioisotopes,
pubmed-meshheading:6771843-Carbamates,
pubmed-meshheading:6771843-Chlorphenamidine,
pubmed-meshheading:6771843-Insecticides,
pubmed-meshheading:6771843-Mannitol,
pubmed-meshheading:6771843-Norepinephrine,
pubmed-meshheading:6771843-Potassium,
pubmed-meshheading:6771843-Rabbits,
pubmed-meshheading:6771843-Time Factors,
pubmed-meshheading:6771843-Tissue Distribution
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pubmed:year |
1980
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pubmed:articleTitle |
The effects of U-40481, demethylchlordimeform, and formetanate on calcium flux in the isolated rabbit aorta.
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pubmed:publicationType |
Journal Article,
In Vitro
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