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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1980-8-28
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pubmed:abstractText |
A large molecular-weight fraction of Pseudomonas aeruginosa culture filtrate protected rats and mice against a lethal infection with a heterologous serotype, and to some extent against Escherichia coli and Listeria monocytogenes. The active components were obtained from cultures grown for several days in a simple synthetic medium. Infection and vaccination with P. aeruginosa serotype 16 induced agglutinating and precipitating antibodies to the components of this serotype only; in rats infected or vaccinated with serotype 1, low titres of agglutinating antibody against type 16 were found. Vaccine prepared from type 1 or 16 increased, within 3 days of infection, the resistance of rats to type-16 organisms; within the same period agglutinins or precipitins were not produced. It is possible that the protection was based on opsonic and antitoxic activities.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0022-2615
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
201-12
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:6770090-Agglutinins,
pubmed-meshheading:6770090-Animals,
pubmed-meshheading:6770090-Antibodies, Bacterial,
pubmed-meshheading:6770090-Bacterial Vaccines,
pubmed-meshheading:6770090-Escherichia coli Infections,
pubmed-meshheading:6770090-Female,
pubmed-meshheading:6770090-Hypersensitivity, Delayed,
pubmed-meshheading:6770090-Leukocyte Count,
pubmed-meshheading:6770090-Macrophages,
pubmed-meshheading:6770090-Male,
pubmed-meshheading:6770090-Mice,
pubmed-meshheading:6770090-Precipitins,
pubmed-meshheading:6770090-Pseudomonas Infections,
pubmed-meshheading:6770090-Pseudomonas aeruginosa,
pubmed-meshheading:6770090-Rats,
pubmed-meshheading:6770090-Vaccination
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pubmed:year |
1980
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pubmed:articleTitle |
Pseudomonas aeruginosa infection and vaccination in the rat.
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pubmed:publicationType |
Journal Article
|