Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1980-6-25
pubmed:abstractText
A spontaneous thiosine-resistant mutant of Escherichia coli was shown to have the following characteristics: lowered initial rate of lysine uptake and lowered plateau level of accumulation of exogenous lysine by both the lysine-specific and the general basic amino acid transport systems; altered repressibility of these two lysine transport systems; a derepressed level of lysine decarboxylase; normal growth rate; parental levels of lysyl-transfer ribonucleic acid synthetase and the inducible and constitutive arginine and ornithine decarboxylases. Both the mutant (lysP) and its parent (lysP+) feed a lysine auxotroph when they are plated in proximity on solid medium. However, the feeding response was observable after 1 day less of incubation when the mutant was the feeding strain. Despite the derepressed level of lysine decarboxylase in exponential cultures of the mutant extracts of these cultures had no detectable cadaverine pool. Conjugation experiments established the following gene order: gyrA (formerly nalA) lysP metG his. All thiosine-resistant recombinants assayed showed reduced lysine transport. In many of these recombinants the derepression of lysine decarboxylase was not expressed.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-1095014, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-1102531, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-14021492, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-14907713, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-15436457, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-163819, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-16747785, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-179582, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-4361275, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-4404468, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-4552089, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-4552550, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-4564714, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-4570607, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-4583243, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-4590109, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-4890230, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-4908780, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-4931309, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-5327656, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-5964978, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-773363, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-786777, http://linkedlifedata.com/resource/pubmed/commentcorrection/6767681-805427
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0021-9193
pubmed:author
pubmed:issnType
Print
pubmed:volume
141
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
485-92
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Escherichia coli regulatory mutation affecting lysine transport and lysine decarboxylase.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.