|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0028040,
umls-concept:C0033567,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0086418,
umls-concept:C0221464,
umls-concept:C0238889,
umls-concept:C0370220,
umls-concept:C1260969,
umls-concept:C1439852,
umls-concept:C1522492
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|
pubmed:issue |
6
|
|
pubmed:dateCreated |
1983-3-24
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|
pubmed:abstractText |
The effects of nicotine and carbon monoxide on the production of PGI2 by rat arterial rings were studied. For PGI2 analysis, we used a bioassay based on platelet-rich plasma aggregation with ADP. Neither nicotine in the incubate nor pretreatment with carbon monoxide decreased PGI2-production as detectable in this bioassay system. Also, neither had a direct effect on the ADP-induced aggregability of human platelet-rich plasma. Consequently, these agents do not seem to be responsible for the temporary increase in platelet aggregability after cigarette smoking.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0098-6127
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:volume |
10
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
412-9
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
|
|
pubmed:year |
1982
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|
pubmed:articleTitle |
Exposure to carbon monoxide or to nicotine does not inhibit PGI2 formation by rat arterial rings incubated with human platelet-rich plasma.
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|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|
