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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
1983-3-11
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pubmed:abstractText |
The anti-pan T cell monoclonal antibody OKT3 was administered daily for 2 weeks in four human renal allograft recipients. The antibody induced a dramatic and immediate depletion of peripheral T cells followed by an in vivo antigenic modulation of the OKT3-defined membrane antigen: after three injections, OKT3-treated patients showed a limited but significant number of OKT3- cells of T cell nature (as defined by OKT4 and OKT8) which recovered the OKT3 receptor after an overnight in vitro incubation in the absence of the monoclonal antibody.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0014-2980
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
979-82
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6759145-Antibodies, Monoclonal,
pubmed-meshheading:6759145-Antigens, Surface,
pubmed-meshheading:6759145-Humans,
pubmed-meshheading:6759145-Immune Tolerance,
pubmed-meshheading:6759145-Immunosuppression,
pubmed-meshheading:6759145-Isoantibodies,
pubmed-meshheading:6759145-Kidney Transplantation,
pubmed-meshheading:6759145-Kinetics,
pubmed-meshheading:6759145-Membrane Proteins,
pubmed-meshheading:6759145-T-Lymphocytes
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pubmed:year |
1982
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pubmed:articleTitle |
Human in vivo antigenic modulation induced by the anti-T cell OKT3 monoclonal antibody.
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pubmed:publicationType |
Journal Article
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