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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1983-2-14
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pubmed:abstractText |
The relative efficacy of sodium and calcium heparin in preventing venous thromboembolism and their relative side-effects were studied in 234 high-risk patients in a randomised, double-blind, placebo-controlled trial. The two heparin preparations were from the same batch and in the same concentration, and were given in a dose of 5000 U 12 hourly. Positive leg scans were found in 19% after placebo, 12% after sodium heparin and 8% after calcium heparin. Bruising at the injection site was more common after calcium heparin (66%) than after sodium heparin (53%) or placebo (38%). Pain at the injection site was also more common after calcium heparin (26%) than after sodium heparin (8%) or placebo (6%). Changes in the activated partial thromboplastin time were small and did not correlate with leg scan results or bruising. While there was a tendency for calcium heparin to be possibly more effective, it was followed by significantly more local haematoma and pain.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0004-8291
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
12
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
501-4
|
pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6758747-Adult,
pubmed-meshheading:6758747-Aged,
pubmed-meshheading:6758747-Calcium,
pubmed-meshheading:6758747-Clinical Trials as Topic,
pubmed-meshheading:6758747-Double-Blind Method,
pubmed-meshheading:6758747-Female,
pubmed-meshheading:6758747-Hematoma,
pubmed-meshheading:6758747-Heparin,
pubmed-meshheading:6758747-Humans,
pubmed-meshheading:6758747-Leg,
pubmed-meshheading:6758747-Male,
pubmed-meshheading:6758747-Middle Aged,
pubmed-meshheading:6758747-Pain,
pubmed-meshheading:6758747-Partial Thromboplastin Time,
pubmed-meshheading:6758747-Random Allocation,
pubmed-meshheading:6758747-Sodium,
pubmed-meshheading:6758747-Thrombophlebitis
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pubmed:year |
1982
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pubmed:articleTitle |
Comparison of sodium and calcium heparin in prevention of venous thromboembolism.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|