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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1982-12-18
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pubmed:abstractText |
This study was undertaken to test a hypothesis that tardive dyskinesia (TD) patients with high plasma dopamine-beta-hydroxylase (DBH) activity would also have other enzymatic alterations suggestive of noradrenergic hyperactivity. Plasma renin activity was chosen as a peripheral indicator of noradrenergic function. We measured plasma renin activity in three groups of female psychiatric inpatients over the age of 50: a TD group with high plasma DBH activity, a TD group with low plasma DBH activity, and a non-TD group. The high-DBH TD group had significantly greater plasma renin activity than the other two groups. Our results are consistent with the hypothesis that a subgroup of TD patients has relative noradrenergic hyperactivity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0271-0749
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
318-20
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6752214-Aged,
pubmed-meshheading:6752214-Blood Pressure,
pubmed-meshheading:6752214-Dopamine beta-Hydroxylase,
pubmed-meshheading:6752214-Dyskinesia, Drug-Induced,
pubmed-meshheading:6752214-Female,
pubmed-meshheading:6752214-Humans,
pubmed-meshheading:6752214-Male,
pubmed-meshheading:6752214-Norepinephrine,
pubmed-meshheading:6752214-Renin
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pubmed:year |
1982
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pubmed:articleTitle |
Enzyme studies in tardive dyskinesia. III. Noradrenergic hyperactivity in a subgroup of dyskinetic patients.
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pubmed:publicationType |
Journal Article
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