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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1982-12-18
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pubmed:abstractText |
Peripheral blast cells from patients with acute lymphoblastic leukaemia were cultured in the diffusion chamber system. On different harvesting days the cALL antigen, surface immunoglobulin and T-cell antigen were investigated by direct immunofluorescence. Each cell type investigated showed a different response throughout culture, the commonest change observed being development into the B-cell axis. Our data demonstrate that the differentiation stop of a leukaemic cell can be overcome by using the diffusion chamber system. The data therefore give some insight into the stage of developmental arrest in acute lymphoblastic leukaemia.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0007-1048
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
319-25
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6751379-Antigens, Neoplasm,
pubmed-meshheading:6751379-B-Lymphocytes,
pubmed-meshheading:6751379-Cell Differentiation,
pubmed-meshheading:6751379-Cells, Cultured,
pubmed-meshheading:6751379-Fluorescent Antibody Technique,
pubmed-meshheading:6751379-Humans,
pubmed-meshheading:6751379-Leukemia, Lymphoid,
pubmed-meshheading:6751379-Phenotype,
pubmed-meshheading:6751379-Receptors, Antigen, B-Cell,
pubmed-meshheading:6751379-T-Lymphocytes,
pubmed-meshheading:6751379-Time Factors
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pubmed:year |
1982
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pubmed:articleTitle |
Acute lymphoblastic leukaemia cells in the diffusion chamber: change of surface phenotype during the culture period.
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pubmed:publicationType |
Journal Article
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