Linked Life Data

6750493

Source:http://linkedlifedata.com/resource/pubmed/id/6750493

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1982-12-2
pubmed:abstractText
Four human eyes, obtained 38 days to 5 years after full-thickness lamellar keratoplasty, were studied by light microscopy for evidence of fibroblast proliferation and collagen formation between the donor Descemet's membrane and the recipient stromal bed. There was delayed healing in the membrane to stroma interface, but at the graft margins a relatively normal stroma-to-stroma healing response was evident. Even in the five-year specimen, bridging of recipient collagen to donor Descemet's membrane was noted only where it was associated with subgraft vascularization. All donor endothelium had disappeared. These studies indicate that in human eyes, retention of Descemet's membrane results in a weaker total graft-host bond than provided by conventional lamellar keratoplasty. In addition, this altered healing may predispose to pseudoanterior chambers that may decrease visual acuity and diminish the theoretical optical advantages of a smooth Descemet's membrane in the graft host interface.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0161-6420
pubmed:author
pubmed:issnType
Print
pubmed:volume
89
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
715-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Full-thickness lamellar keratoplasty. A histologic study in human eyes.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't