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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1982-12-2
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pubmed:abstractText |
The results of allogeneic marrow transplantation in 75 patients with acute lymphoblastic leukemia and 63 patients with acute non-lymphoblastic leukemia in relapse are reviewed. The effects of various chemotherapeutic regimens added to the basic regimen of cyclophosphamide (Cy) 60 mg/kg given on each of two successive days followed by 1000 rad of total body irradiation (TBI) were evaluated. The regimens tested were dimethylbusulphan (DMB), 1,3-bis(2-chlorethyl)-1-nitrosourea (BCNU) and daunorubicin. Seventeen of 138 patients are alive between three and nine and a half years from transplantation. The addition of other chemotherapeutic agents to th basic Cy and TBI regimen did not decrease relapse frequency or prolong survival.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0145-2126
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
383-7
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6750250-Adolescent,
pubmed-meshheading:6750250-Adult,
pubmed-meshheading:6750250-Bone Marrow Transplantation,
pubmed-meshheading:6750250-Child,
pubmed-meshheading:6750250-Child, Preschool,
pubmed-meshheading:6750250-Cyclophosphamide,
pubmed-meshheading:6750250-Follow-Up Studies,
pubmed-meshheading:6750250-Humans,
pubmed-meshheading:6750250-Infant,
pubmed-meshheading:6750250-Leukemia,
pubmed-meshheading:6750250-Leukemia, Lymphoid,
pubmed-meshheading:6750250-Middle Aged,
pubmed-meshheading:6750250-Recurrence,
pubmed-meshheading:6750250-Whole-Body Irradiation
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pubmed:year |
1982
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pubmed:articleTitle |
Allogeneic marrow transplantation for acute leukemia in relapse.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
|