|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0043393,
umls-concept:C0314627,
umls-concept:C0596988,
umls-concept:C0680730,
umls-concept:C1148554,
umls-concept:C1155789,
umls-concept:C1373200,
umls-concept:C1546465,
umls-concept:C1704259,
umls-concept:C1705175,
umls-concept:C1705176,
umls-concept:C1705177,
umls-concept:C1705178,
umls-concept:C1705987,
umls-concept:C1882348
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
1982-12-2
|
|
pubmed:abstractText |
Cold-sensitive (cs) and heat-sensitive (ts) conditional-lethal mutations that affect specifically the cell division cycle of budding yeast (Saccharomyces cerevisiae) were used to determine the order of gene function. Reciprocal temperature-shift experiments using cs-ts double mutants revealed a detailed order of function among genes whose execution points and mutant phenotypes are very similar. The data suggest that the nuclear branch of the overall cell-cycle pathway itself contains at least one branch.
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pubmed:grant |
|
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pubmed:commentsCorrections |
|
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
0016-6731
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:volume |
100
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
565-77
|
|
pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
|
|
pubmed:year |
1982
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|
pubmed:articleTitle |
Determination of the order of gene function in the yeast nuclear division pathway using cs and ts mutants.
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|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
