Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1984-9-12
pubmed:abstractText
The composition of glomerulosclerosis was examined in focal sclerosis, membranoproliferative glomerulonephritis, and crescentic glomerulonephritis, using antisera specific for laminin and collagen types III and IV. Mesangial sclerosis consisted exclusively of extracellular matrix found in normal glomeruli, as did small synechiae in focal sclerosis and all synechiae in membranoproliferative glomerulonephritis. The large synechiae in focal sclerosis and all stages of the developing crescents associated with vasculitis contained mainly interstitial collagen, type III, a component not found in normal glomeruli. In the latter there were also disruptions of Bowman's capsule and an increase in the number of periglomerular interstitial cells. These observations suggested that glomerulosclerosis varied in composition and distribution, and some types of crescentic glomerulonephritis may have arisen from either cells resident in the glomerulus or cells coming from the interstitial space.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0023-6837
pubmed:author
pubmed:issnType
Print
pubmed:volume
51
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
181-92
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
The composition of glomerulosclerosis. I. Studies in focal sclerosis, crescentic glomerulonephritis, and membranoproliferative glomerulonephritis.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't