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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1984-9-17
|
| pubmed:abstractText |
An androgen binding species has been identified in partially purified cytosol from human thymic tissue, resolved from sex steroid binding globulin by gel chromatography. This putative 5 alpha-dihydrotestosterone receptor was characterised by high affinity (Kd 6.7 X 10(-10) M) and low capacity (9 fmol/mg of cytosol protein). High affinity binding was confirmed with methyltrienolone (R1881). Competition studies were carried out with a number of androgenic compounds and 5 alpha-19 nordihydrotestosterone was shown to possess the highest affinity for the androgen receptor.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0165-2478
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
8
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
49-53
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:6746015-Adult,
pubmed-meshheading:6746015-Androgens,
pubmed-meshheading:6746015-Cytosol,
pubmed-meshheading:6746015-Dihydrotestosterone,
pubmed-meshheading:6746015-Humans,
pubmed-meshheading:6746015-Receptors, Androgen,
pubmed-meshheading:6746015-Receptors, Steroid,
pubmed-meshheading:6746015-Thymus Gland
|
| pubmed:year |
1984
|
| pubmed:articleTitle |
Androgen receptor in the human thymus.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|