Linked Life Data

6745258

Source:http://linkedlifedata.com/resource/pubmed/id/6745258

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1984-9-5
pubmed:abstractText
Two conformations of the 5.8S rRNA have been distinguished by gel electrophoresis. Diethyl pyrocarbonate and dimethyl sulphate reactivity were used to probe these conformational states in both the free molecule and those associated with 28S RNA or the ribosome. Both conformations could be demonstrated in each case and in every instance four residues, C50, A52, G53, C54, which were strongly reactive in the faster-migrating conformation were essentially unreactive in the slower-migrating form. These results suggest that the two conformations differ in the degree to which the tertiary structure is folded and raise the possibility that the 5.8S rRNA functions in translation by switching between alternative conformational states.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0014-2956
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
141
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
549-53
pubmed:dateRevised
2007-7-23
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Alternative conformational states in the ribosome-associated 5.8S RNA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't