Linked Life Data

6743382

Source:http://linkedlifedata.com/resource/pubmed/id/6743382

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
1984-8-2
pubmed:abstractText
We have investigated serum lipids, lipoproteins and apolipoprotein levels in 97 survivors of acute myocardial infarction in order to clarify the characteristics of lipid and lipoprotein disorders in coronary artery disease among Japanese. Although the HDL cholesterol level was lower and the atherogenic index was higher in the myocardial infarction (MI) group than in the control group, in agreement with previous papers, there was no significant difference in total serum cholesterol level between the MI and the control groups. On the other hand, the triglyceride level was significantly higher in the MI group. The MI group also had higher levels of both cholesterol and triglyceride in the VLDL fraction (d less than 1.006) with a statistically significant increase in the ratio of cholesterol to triglyceride compared with the control group. Levels of both lipids in the IDL fraction (1.006 less than d less than 1.019) were higher in the MI group than in the control group. Lipoprotein analysis with PAG disc electrophoresis revealed a more frequent occurrence of a "midband", which appeared as an additional band between the LDL and VLDL positions, in the MI group than in the control group (MI:51% versus control: 25%, P less than 0.02). The midband-positive subgroup had a higher ratio of cholesterol to triglyceride in the VLDL fraction and higher levels of both lipids in the IDL fraction. Isoelectric focusing of apo VLDL revealed that the incidence of the suspected apo E-ND (E3/2 or E4/2) constitution, which was determined by a low ratio (less than 1.1) of the peak area of E3 to that of E2, was three times higher in the MI group than in the control group (MI:25% versus control: 7%).(ABSTRACT TRUNCATED AT 250 WORDS)
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0021-9150
pubmed:author
pubmed:issnType
Print
pubmed:volume
51
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
241-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Increased frequency of lipoprotein disorders similar to type III hyperlipoproteinemia in survivors of myocardial infarction in Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't