Linked Life Data

6743082

Source:http://linkedlifedata.com/resource/pubmed/id/6743082

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1984-8-1
pubmed:abstractText
We measured visual fields using three unconventional test stimuli; sine-wave grating targets of 2 and 5 cycles/degree and a visual acuity target. Of 15 patients with ocular hypertension (OHT), eight had visual field defects for contrast sensitivity when tested with a sine-wave grating target of low spatial frequency; these patients had normal perimetric fields and normal fields for visual acuity. We hypothesize that the outer extremities of the largest dendritic trees of retinal ganglion cells become functionally ineffective in some patients with OHT and early glaucoma, possibly due to retinal ischemia, and as a result visual sensitivity to low spatial frequency gratings is reduced while visual acuity is spared. Since this hypothetical mechanism may be somewhat independent of the mechanism that causes ganglion cell loss, not all the contrast field defects in OHT would be expected to progress to glaucomatous field defects and be evident to clinical perimetry.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0003-9950
pubmed:author
pubmed:issnType
Print
pubmed:volume
102
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1042-5
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Visual field defects in ocular hypertension and glaucoma.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't