Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1984-8-22
pubmed:abstractText
Mocha mice with pigment anomalies of the coat, eyes, and inner ears also have congenital otolith defects, and they exhibit progressive cochlear degeneration. Mocha mice were first reported to exhibit otolith defects comparable to those of pallid mice. Since manganese supplementation is effective in preventing the otolith defects in pallid mice and in pastel mink, we sought to establish whether or not manganese also might be effective in mocha mice. The otolith defects of mocha mice were prevented or reduced by supplementing the pregnant dams with manganese and/or zinc. The mocha mice also exhibited high perinatal mortality that was not reduced by the supplementary metals. Surviving mocha mice have behavioral anomalies associated with their inner ear defects. Preliminary observations of auditory-evoked brainstem responses and of cochlear degeneration in the mocha mice are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0022-1503
pubmed:author
pubmed:issnType
Print
pubmed:volume
75
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
159-62
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Trace metals and otolith defects in mocha mice.
pubmed:publicationType
Journal Article, Comparative Study