Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
1984-7-30
pubmed:abstractText
We identified 2 potent proteins with inhibiting activities of platelet aggregation and blood coagulation from the human placenta. Ultracentrifugation of placental homogenate showed that these proteins are incorporated in the microsomal membrane. These proteins were solubilized in Triton X-100 by means of sonication. The inhibitors were purified by several steps of chromatography and gel filtration in a single band on polyacrylamide gel electrophoresis, having molecular weights of 450 000 and 45 000. The aggregation inhibitor was different from inhibitors reported previously such as phosphatase and prostacyclin-like substance. The coagulation inhibitor was capable of inactivating tissue thromboplastin.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0301-2115
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
149-54
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Inhibitors of platelet aggregation and blood coagulation isolated from the human placenta.
pubmed:publicationType
Journal Article