|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
1984-8-15
|
|
pubmed:abstractText |
The biliary excretion of 14C-phenylcyclohexene and its metabolites were studied in rats pretreated with an inducer or inhibitor of mixed-function oxidases or with an agent known to deplete liver glutathione. Pretreatment of rats with 3-methylcholanthrene or phenobarbital enhanced the biliary excretion of 14C-phenylcyclohexene and/or its metabolites. Conversely, pretreatment of rats with SKF-525A or piperonyl butoxide decreased the biliary excretion of 14C-phenylcyclohexene and/or its metabolites. In contrast, pretreatment of rats with diethylmaleate did not alter significantly the rate of biliary excretion of radioactivity.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0148-0545
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
7
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
273-82
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:6734467-Animals,
pubmed-meshheading:6734467-Bile,
pubmed-meshheading:6734467-Cyclohexanes,
pubmed-meshheading:6734467-Enzyme Induction,
pubmed-meshheading:6734467-Glutathione,
pubmed-meshheading:6734467-Kinetics,
pubmed-meshheading:6734467-Male,
pubmed-meshheading:6734467-Maleates,
pubmed-meshheading:6734467-Methylcholanthrene,
pubmed-meshheading:6734467-Mixed Function Oxygenases,
pubmed-meshheading:6734467-Phenobarbital,
pubmed-meshheading:6734467-Piperonyl Butoxide,
pubmed-meshheading:6734467-Proadifen,
pubmed-meshheading:6734467-Rats,
pubmed-meshheading:6734467-Rats, Inbred Strains,
pubmed-meshheading:6734467-Time Factors
|
|
pubmed:year |
1984
|
|
pubmed:articleTitle |
Effects of drug and chemical pretreatments on biliary excretion of phenylcyclohexene in the rat.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
