Linked Life Data

672929

Source:http://linkedlifedata.com/resource/pubmed/id/672929

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1978-9-29
pubmed:abstractText
The dose-dependent effects of triethylenemelamine (TEM) on fertility and the induction of chromosomal translocation in treated mice and their F1 sons were examined C3H mice were treated with TEM for 8 successive weeks at doses of 0.02 and 0.04 mg/kg of body weight. All males treated with TEM were fertile,and cytological analysis of meiotic cells showed no chromosomal rearrangements. Semi-sterility and sterility were noted in F1 sons of TEM-treated animals. This semi-sterility and sterility were associated with reciprocal translocations. The percentage of animals heterozygous for translocations was higher for F1 males originating from sires treated with TEM at 0.04 mg/kg than from sires treated with 0.02 mg/kg.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0027-5107
pubmed:author
pubmed:issnType
Print
pubmed:volume
54
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
55-60
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
An analysis of meiotic chromosomes of inbred male mice and their F1 sons after long-term treatment of sires with triethylenemelamine.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.