Linked Life Data

6727702

Source:http://linkedlifedata.com/resource/pubmed/id/6727702

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1984-7-13
pubmed:abstractText
Using a double infusion technique described in the previous paper, the effect of shear rate, G, on platelet aggregation was studied in citrated platelet-rich plasma in Poiseuille flow over a range of mean linear flow rates, u3 from 50 to 1500 microns-1 corresponding to G from 2 to 54 sec-1. At 1 micron ADP, aggregates were formed at all u3 and, except at the lowest flow rate, both the degree of aggregation (net fraction of cells in aggregates, A') and size of the aggregates increased with distance down the tube. The degree of aggregation was both time and shear rate-dependent. Over the first 10 sec, A' appeared to be independent of the mean transit time indicating that the collision capture efficiency decreased with increasing G. Thereafter, A' increased with increasing shear rate leading to the formation of an appreciable number of aggregates greater than 10 cells at G greater than 24 sec-1. Small aggregates initially formed near the tube wall and, as they grew in size, migrated toward the axis as their rotation was physically impeded by the wall. In addition, the values of A' in cPRP from five female donors were significantly greater than those from five male donors.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0026-2862
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
316-30
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Platelet aggregation in poiseuille flow: II. Effect of shear rate.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't