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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1984-7-2
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pubmed:abstractText |
Forty-five oocyte-corona-cumulus complexes ( OCCC ) were obtained from follicles of 13 women undergoing fertilization in vitro. Follicular growth was induced with human menopausal gonadotropin, and follicular aspiration was performed 36 h after an ovulatory injection of hCG. The maturation of these complexes was evaluated by the extent of cumulus mucification and corona cell dispersal. Three main morphological types were characterized: immature OCCCs (6), with a tight and compact corona-cumulus mass surrounding the oocyte; intermediate OCCCs (26), with a dispersed cumulus but only partly dispersed corona layer; and mature complexes (13) with complete dispersal of both cellular components. During a 24-h culture, progesterone secretion by intermediate and mature OCCCs was 30-fold higher (mean +/- SEM, 652 +/- 87 ng/ OCCC X 24 h) than immature OCCCs (19.6 +/- 3.5 ng/ OCCC X 24 h), while estradiol secretion was twice as high (3.8 +/- 1.1 vs. 1.2 +/- 0.6 ng/ OCCC X 24 h). Testosterone secretion was similar in all three types of OCCCs cultured (0.30 ng/24 h). It is suggested that the steroids produced by the OCCC may contribute to the local milieu of the fallopian tube.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0021-972X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
58
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1153-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6725511-Adult,
pubmed-meshheading:6725511-Cells, Cultured,
pubmed-meshheading:6725511-Estradiol,
pubmed-meshheading:6725511-Female,
pubmed-meshheading:6725511-Fertilization in Vitro,
pubmed-meshheading:6725511-Gonadal Steroid Hormones,
pubmed-meshheading:6725511-Humans,
pubmed-meshheading:6725511-Oocytes,
pubmed-meshheading:6725511-Ovarian Follicle,
pubmed-meshheading:6725511-Ovulation,
pubmed-meshheading:6725511-Progesterone,
pubmed-meshheading:6725511-Testosterone
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pubmed:year |
1984
|
pubmed:articleTitle |
Steroid secretion by the human egg-corona-cumulus complex in culture.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|