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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1984-6-25
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pubmed:abstractText |
The accuracy of a pencil-beam algorithm for electrons employing a two-dimensional heterogeneity correction is demonstrated by comparing calculation with measurement. Ionization measurements have been made in a water phantom for a variety of non-standard geometries. Geometries to demonstrate the effect of an extended treatment distance, a sloping skin surface, and an irregular skin surface have been selected. Additionally, thermoluminescent dosimeters have been used to measure distributions in tissue-substitute phantoms, which were designed from individual patient computerized tomographic scans. Three patient scans have been selected: (1) diffuse hystiocytic lymphoma of the left buccal mucosa and retromolar trigone; (2) squamous cell carcinoma of the nose at the columnella ; and (3) carcinoma of the maxillary antrum. Results demonstrate the algorithm's ability to simultaneously account for the isodose shifting as a result of internal heterogeneities and for sidescatter non-equilibrium caused by lateral discontinuities of the skin surface and internal anatomy. The algorithm is shown to generally be accurate to within +/- 4% in the treatment volume or +/- 4 mm in regions of sharp dose gradients as found in the penumbra and distal edge of the beam. Examples of greater disagreement are shown and their physical interpretation discussed.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0360-3016
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
561-9
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6725043-Carcinoma, Squamous Cell,
pubmed-meshheading:6725043-Computers,
pubmed-meshheading:6725043-Electrons,
pubmed-meshheading:6725043-Humans,
pubmed-meshheading:6725043-Mathematics,
pubmed-meshheading:6725043-Models, Structural,
pubmed-meshheading:6725043-Mouth Neoplasms,
pubmed-meshheading:6725043-Nose Neoplasms,
pubmed-meshheading:6725043-Radiation Monitoring,
pubmed-meshheading:6725043-Thermoluminescent Dosimetry,
pubmed-meshheading:6725043-Tissue Distribution,
pubmed-meshheading:6725043-Tomography, X-Ray Computed,
pubmed-meshheading:6725043-Water
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pubmed:year |
1984
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pubmed:articleTitle |
Dosimetric evaluation of a pencil-beam algorithm for electrons employing a two-dimensional heterogeneity correction.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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