Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-6-18
pubmed:abstractText
The effect of bradykinin on bone resorption was studied in cultures of newborn-mouse calvaria. Bradykinin (0.03 microM, 1 microM) stimulated the release of 45Ca2+ from bones dissected out from mice prelabelled in vivo with 45Ca. Bradykinin (1 microM) also augmented the release of stable calcium ( 40Ca ), Pi and the lysosomal enzyme beta-glucuronidase. The stimulatory effect of bradykinin on mineral mobilization and lysosmal -enzyme release could be blocked by indomethacin. It is speculated that concomitant generation of thrombin and bradykinin in areas of trauma and inflammation may induce resorption of nearby bone tissue.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-1054489, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-13273400, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-14338851, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-16749142, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-219372, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-361756, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-37257, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-384593, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-4315103, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-4543513, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-4580465, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-494155, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-5052733, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-5328155, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-6127164, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-6172485, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-6352100, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-6774443, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-6810948, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-6860783, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-6943971, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-7007500, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-7015371, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-7150243, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-7180734, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-7417523, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-7439388, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-748028, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-874082, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-942951, http://linkedlifedata.com/resource/pubmed/commentcorrection/6721862-965390
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0264-6021
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
219
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
329-32
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Bradykinin stimulates bone resorption and lysosomal-enzyme release in cultured mouse calvaria.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't