Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1984-6-14
pubmed:abstractText
To help individual prediction of the therapy efficacy, the authors elaborated a new method for analyzing the response of the clinical and pharmacokinetic parameters to the pre-treatment administration of the test dose of a psychotropic drug. The above approach was employed in a multicentre clinical-pharmacokinetic study of leponex ( clozapin ) which involved ten research centers from six countries and a total of 136 patients. On the basis of the clinical and pharmacokinetic parameters, a cumulative index was obtained and its prediction potentialities were established. The prognostic assessment of the affectiveness obtained on the basis of this approach was in agreement with the real efficacy of the course therapy in 84% of all cases.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0044-4588
pubmed:author
pubmed:issnType
Print
pubmed:volume
84
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
401-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
[Clinico-pharmacokinetic prediction of the efficacy of treatment: the test dose].
pubmed:publicationType
Journal Article, English Abstract