Linked Life Data

6718456

Source:http://linkedlifedata.com/resource/pubmed/id/6718456

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1984-6-5
pubmed:abstractText
Stress induced analgesia (SIA) and stress-induced changes in body temperature were studied in mice and rats. Immobilization was used as the stressor. Nociception was measured with the tail-flick method and body temperature was recorded in the colon. Within 5 min of immobilization a similar increase in tail-flick latencies was observed in the two species. Concomitantly, the body temperature increased in the rats and decreased in the mice. Transection of the spinal cord 7 days before the experiments tended to increase the effect of stress on the tail-flick latencies in both species. Pretreatment with naloxone HCL (2 mg/kg SC, 5 min before immobilization) did not influence SIA in either intact or spinal rats. Thus, analgesia induced by immobilization may be due to a non-opioid substance acting peripherally or reaching the spinal cord via the systemic circulation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0091-3057
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
289-92
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Immobilization-induced analgesia: possible involvement of a non-opioid circulating substance.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't