Linked Life Data

6716047

Source:http://linkedlifedata.com/resource/pubmed/id/6716047

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1984-6-7
pubmed:abstractText
The changing nature of intercellular coupling during the 4- and 8-cell stages of mouse early development has been investigated by iontophoretic injection of carboxyfluorescein, horseradish peroxidase and current into individual blastomeres in either the intact embryo or after their disaggregation and reaggregation into pairs. Coupling junctions that allowed only molecules of low molecular weight (putative gap junctions) were found not to appear until 2-5 h beyond the 3rd cleavage division (8-cell stage). However, intercellular junctions that were not size selective were detected in intact embryos only throughout the 4- and 8-cell stages. It is proposed that this junctional communication results from the persistence of midbodies through all or part of the two, and in a few cases the three, cell cycles following their formation at the first and second cleavage divisions. We conclude that the cells of the early mouse embryo may be linked in a more extensive syncytial network than was hitherto suspected.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0022-0752
pubmed:author
pubmed:issnType
Print
pubmed:volume
79
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
53-76
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
The nature of intercellular coupling within the preimplantation mouse embryo.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't