Linked Life Data

6715868

Source:http://linkedlifedata.com/resource/pubmed/id/6715868

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1984-6-20
pubmed:abstractText
The henny -feathering trait of the Sebright bantam chicken is the result of an enhanced rate of estrogen synthesis (aromatase activity) in skin and other peripheral tissues of this bird. To gain insight into the underlying nature of this mutation, we examined the inheritance of this trait using a sensitive isotopic assay for aromatase activity. All birds of the F1 generation obtained by crossing homozygous henny X non- henny chickens expressed increased aromatase in the skin, and the males exhibited henny -feathering plumage. The average rate of aromatase activity in the skin of F1 chicks was approximately half that of homozygous henny chicks. The distribution of increased aromatase activity in the F2 generation and in the backcrosses of F1 to the two types of parental strains suggest that the enzyme activity in extragonadal tissues is regulated predominantly by one autosomal gene. Attempts to demonstrate linkage to several known loci by backcrossing F1 heterozygotes with parental chickens carrying a variety of genetic markers were unsuccessful. We conclude that the enhanced estrogen synthesis in extragonadal tissues in chickens carrying this gene is inherited as an autosomal codominant but that a half maximal level of the enzyme is sufficient to allow full development of female feathering in affected male birds so that henny -feathering is transmitted as a dominant trait.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0022-1503
pubmed:author
pubmed:issnType
Print
pubmed:volume
75
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
99-102
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:articleTitle
Inheritance of the henny-feathering trait of the Sebright bantam chicken.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't