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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1984-6-1
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pubmed:abstractText |
The authors conducted an investigation in order to ascertain whether or not L-carnitine, by promoting the utilization of FFA for energy and neutralizing FFA toxicity occurring after ischaemia, could prevent or confine adriamycin-induced cardiotoxicity in rabbits. The results show that L-carnitine determines a higher survival rate and reduced onset of cardiomyopathy. Histopathological examination of myocardial tissue under light and electron microscopy revealed a marked decrease in mitochondrial lesions.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0250-0868
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
91-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6715123-Animals,
pubmed-meshheading:6715123-Cardiomyopathies,
pubmed-meshheading:6715123-Carnitine,
pubmed-meshheading:6715123-Doxorubicin,
pubmed-meshheading:6715123-Male,
pubmed-meshheading:6715123-Mitochondria, Heart,
pubmed-meshheading:6715123-Myocardium,
pubmed-meshheading:6715123-Rabbits
|
pubmed:year |
1984
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pubmed:articleTitle |
Effects of L-carnitine on adriamycin-induced cardiomyopathy in rabbit.
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pubmed:publicationType |
Journal Article,
Comparative Study
|