Linked Life Data

6714298

Source:http://linkedlifedata.com/resource/pubmed/id/6714298

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-6-6
pubmed:abstractText
In ten anesthetized pigs, nisoldipine (2-4 micrograms X kg-1 X min-1), a calcium channel blocker structurally related to nifedipine, reduced left ventricular systolic pressure (40%) and systemic vascular resistance (35%), whereas maxLVdP/dt decreased by 20% and cardiac output was unchanged. Left ventricular end-diastolic volume (15%) and end-diastolic pressure (40%) decreased, while ejection fraction slightly increased (13%). In normal hearts, nisoldipine reduces left ventricular pre- and afterload, without a depression of myocardial contractility, which results in a more efficient emptying of the left ventricle.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0014-2999
pubmed:author
pubmed:issnType
Print
pubmed:day
10
pubmed:volume
98
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
137-40
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Is nisoldipine capable of reducing left ventricular preload?
pubmed:publicationType
Journal Article