Linked Life Data

6713379

Source:http://linkedlifedata.com/resource/pubmed/id/6713379

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1984-6-1
pubmed:abstractText
Thermal dose-survival curves for normal hematopoietic and leukemia cells were assessed by spleen colony assays after in vitro heat exposure ranging from 41 degrees to 45 degrees. No effect of 43 degrees heat treatment on the fraction of cells lodging in the spleen was observed. Marked differences in heat sensitivity were observed between normal, L1210, and AKR leukemia cells, the first being les sensitive than were the malignant cells. Furthermore, a greater relative difference between normal stem cells and leukemia cells was observed at lower temperatures. Normal bone marrow cells forced into regenerative activity prior to heat treatment were more heat sensitive than was their undisturbed counterpart, suggesting that noncycling hematopoietic cells are less heat sensitive than are proliferating cells.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0008-5472
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1761-6
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Differential effect of hyperthermia on murine bone marrow normal colony-forming units and AKR and L1210 leukemia stem cells.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't