Linked Life Data

6711385

Source:http://linkedlifedata.com/resource/pubmed/id/6711385

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1984-5-24
pubmed:abstractText
To determine the properties of rat gastric cells involved in histamine metabolism (histaminocytes), fundic mucosa was enzymatically dispersed prior to separation by sedimentation methods. The distribution of histamine content, histidine decarboxylase (HDC) activity and incorporation of radioactive histidine metabolites were used to determine the characteristics of various populations of gastric cells. All activities measured, as well as most of the dispersed gastric cells, occurred in a narrow range of density between 1.083 and 1.091 g/ml. Velocity sedimentation showed that two populations of histaminocytes can be distinguished. One population has a higher sedimentation rate, suggesting a larger size, contains histamine, HDC activity and incorporates radioactive metabolites. Another population, in fractions with lower sedimentation rates, contains little histamine, has a higher HDC activity than the previous population and also incorporates radiolabelled histidine metabolites. For the first time, two populations of viable histaminocytes have been separated that differ in their biochemical properties.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0065-4299
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
185-94
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Separation and characteristics of two histaminocytes from rat gastric mucosa.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't