rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
1984-5-11
|
pubmed:abstractText |
The effects of intrajejunal and intravenous infusion of fat (100 ml Intralipid 20%) on pentagastrin-stimulated gastric acid secretion and on the concentrations of plasma neurotensin-like immunoreactivity (p-NTLI) were studied in eight healthy subjects. Gastric acid secretion was studied for a 1.5-h period at 15-min intervals after fat administration. Acid secretion was reduced by 58% and 36%, respectively, after intrajejunal and intravenous administration. The concentration of p-NTLI rose significantly from 29 to 177 pmol/l at 45 min after intrajejunal administration but did not change after intravenous infusion. The results indicate that large volumes of fat inhibit gastric acid secretion by a neurotensin-independent postabsorptive mechanism and by an intestinal mechanism that may in part be mediated by neurotensin.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0036-5521
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
19
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
48-51
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:6710077-Adult,
pubmed-meshheading:6710077-Fat Emulsions, Intravenous,
pubmed-meshheading:6710077-Fats,
pubmed-meshheading:6710077-Female,
pubmed-meshheading:6710077-Gastric Acid,
pubmed-meshheading:6710077-Humans,
pubmed-meshheading:6710077-Jejunum,
pubmed-meshheading:6710077-Male,
pubmed-meshheading:6710077-Middle Aged,
pubmed-meshheading:6710077-Nerve Tissue Proteins,
pubmed-meshheading:6710077-Neuropeptides,
pubmed-meshheading:6710077-Pentagastrin,
pubmed-meshheading:6710077-Time Factors
|
pubmed:year |
1984
|
pubmed:articleTitle |
Effect of intravenous and intrajejunal fat infusion on gastric acid secretion and plasma neurotensin-like immunoreactivity in man.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|