Linked Life Data

6709642

Source:http://linkedlifedata.com/resource/pubmed/id/6709642

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1984-5-2
pubmed:abstractText
The lower incisors of Male Wistar rats flown for 18.5 days on the Soviet Cosmos-1129 Biosatellite were sectioned and chemically analyzed with an electron microprobe in order to determine whether there were specific effects of spaceflight on dentin formation/mineralization. Control tissues were obtained from rats housed under identical conditions in a land-based mock-up of the Biosatellite. The profiles of calcium (Ca), phosphorus (P), and sulfur (S) concentrations in dentin were measured in continuous traverses (1.0 micron intervals) from the pulp to the dentinoenamel junction. The incisor dentin formed during spaceflight had higher than normal (at 1G) concentrations of Ca (+ 10-15%) and P (+ 20-30%), particularly in the temporally youngest tissues within 80 micron of the pulp which had been least affected by secondary mineralization. The S-concentration profiles tended to decrease with tissue age. Fourier analysis (to determine the growth rhythms) revealed abnormal distributional patterns of S in the recently formed dentin from the Flight rats. The sulfur fluctuations in Flight animals alone periodically peaked above the irregular background fluctuations. These observations indicate that spaceflight has measureable effects on dentinogenesis, and they may also bear on the problem of the regulatory role of proteoglycans in mineralization and in the maturation of mineral and matrix moieties in skeletal tissue.
pubmed:keyword
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0037-9727
pubmed:author
pubmed:issnType
Print
pubmed:volume
175
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
429-37
pubmed:dateRevised
2007-11-2
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
The effects of spaceflight on the mineralization of rat incisor dentin.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.