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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1984-4-11
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pubmed:abstractText |
Serum bactericidal activity was determined routinely in 89 patients with gram-negative bacillary bacteremia, 79 of whom were analyzed because they had granulocyte counts either below 100/mm3 or above 1,000/mm3. A peak (one hour after the administration of the antibiotics) serum bactericidal titer of 1:8 or more in non-granulocytopenic patients or 1:16 or more in severely granulocytopenic patients could be correlated with a favorable clinical response, in 98 percent (44 of 45) (p less than 0.0001) and 87 percent (20 of 23), (p less than 0.001) respectively. Granulocytopenic patients required a statistically significantly higher serum bactericidal activity for a favorable response. Serum bactericidal activity appears to be a useful and simple method to monitor antibiotic treatment in gram-negative bacillary bacteremia, especially when combination therapy is used.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0002-9343
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
429-35
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6702874-Agranulocytosis,
pubmed-meshheading:6702874-Bacterial Infections,
pubmed-meshheading:6702874-Blood Bactericidal Activity,
pubmed-meshheading:6702874-Gram-Negative Bacteria,
pubmed-meshheading:6702874-Humans,
pubmed-meshheading:6702874-Leukemia,
pubmed-meshheading:6702874-Leukocyte Count,
pubmed-meshheading:6702874-Neutropenia,
pubmed-meshheading:6702874-Outcome and Process Assessment (Health Care)
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pubmed:year |
1984
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pubmed:articleTitle |
Significance of serum bactericidal activity in gram-negative bacillary bacteremia in patients with and without granulocytopenia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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