Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-4-3
pubmed:abstractText
The effect of dietary cod-liver oil on factors which characterize membrane lipid fluidity was studied. To six volunteers a daily supplement of 15 ml of cod-liver oil, providing 3 g of omega 3 fatty acids, was given for 2 weeks. Changes induced by the supplement in the fatty acid patterns of the individual erythrocyte phospholipid classes did not occur at the same rate or in the same degree. A rapid incorporation of omega 3 fatty acids in plasma lipids and in erythrocyte phosphatidyl choline, at the expense of linoleic acid, was seen, resulting in increased total unsaturation. A slower and quantitatively smaller incorporation of omega 3 fatty acids in erythrocyte phosphatidyl ethanolamine and phosphatidyl serine was seen. No change in the fatty acid pattern of sphingomyelin was seen. Withdrawal of the supplement for 2 weeks did partly reverse the cod-liver oil induced changes in erythrocyte phosphatidyl choline, while the changes in erythrocyte phosphatidyl ethanolamine and phosphatidyl serine lasted. Neither a change in distribution of erythrocyte phospholipid classes, nor in the erythrocyte cholesterol/phospholipid ratio was found. The observed changes in lipid composition are indicative of an increased lipid fluidity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0036-5513
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
39-46
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Effect of dietary cod-liver oil on the lipid composition of human erythrocyte membranes.
pubmed:publicationType
Journal Article