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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1984-4-3
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pubmed:abstractText |
The effect of dietary cod-liver oil on factors which characterize membrane lipid fluidity was studied. To six volunteers a daily supplement of 15 ml of cod-liver oil, providing 3 g of omega 3 fatty acids, was given for 2 weeks. Changes induced by the supplement in the fatty acid patterns of the individual erythrocyte phospholipid classes did not occur at the same rate or in the same degree. A rapid incorporation of omega 3 fatty acids in plasma lipids and in erythrocyte phosphatidyl choline, at the expense of linoleic acid, was seen, resulting in increased total unsaturation. A slower and quantitatively smaller incorporation of omega 3 fatty acids in erythrocyte phosphatidyl ethanolamine and phosphatidyl serine was seen. No change in the fatty acid pattern of sphingomyelin was seen. Withdrawal of the supplement for 2 weeks did partly reverse the cod-liver oil induced changes in erythrocyte phosphatidyl choline, while the changes in erythrocyte phosphatidyl ethanolamine and phosphatidyl serine lasted. Neither a change in distribution of erythrocyte phospholipid classes, nor in the erythrocyte cholesterol/phospholipid ratio was found. The observed changes in lipid composition are indicative of an increased lipid fluidity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol Esters,
http://linkedlifedata.com/resource/pubmed/chemical/Cod Liver Oil,
http://linkedlifedata.com/resource/pubmed/chemical/Fish Oils,
http://linkedlifedata.com/resource/pubmed/chemical/Lipids,
http://linkedlifedata.com/resource/pubmed/chemical/Phospholipids,
http://linkedlifedata.com/resource/pubmed/chemical/Triglycerides
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0036-5513
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
39-46
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6701449-Adult,
pubmed-meshheading:6701449-Cell Membrane,
pubmed-meshheading:6701449-Cholesterol,
pubmed-meshheading:6701449-Cholesterol Esters,
pubmed-meshheading:6701449-Cod Liver Oil,
pubmed-meshheading:6701449-Erythrocytes,
pubmed-meshheading:6701449-Fish Oils,
pubmed-meshheading:6701449-Humans,
pubmed-meshheading:6701449-Lipids,
pubmed-meshheading:6701449-Middle Aged,
pubmed-meshheading:6701449-Phospholipids,
pubmed-meshheading:6701449-Triglycerides
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pubmed:year |
1984
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pubmed:articleTitle |
Effect of dietary cod-liver oil on the lipid composition of human erythrocyte membranes.
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pubmed:publicationType |
Journal Article
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