Linked Life Data

6699554

Source:http://linkedlifedata.com/resource/pubmed/id/6699554

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-4-24
pubmed:abstractText
It is known that excessive alcohol consumption leads to changes in clinical chemical and haematological parameters that are reversed to a greater or lesser degree after alcohol consumption ceases. Such factors that lead to changes in vivo in the parameters studied are termed biological influence factors. In the study reported here the biological influence factor "excessive alcohol consumption" was assessed in its most severe form, namely alcoholism. To this end 24 clinical chemical parameters and 8 haematological parameters were studied in 82 male alcoholics. The diagnoses of alcohol abuse and alcoholism were made on the basis of the Munich Alcoholism Test (MALT) and the information obtained in the following standardized interviews and examinations: past history, an alcohol questionnaire, general physical examination and neurological examination. All forms were filled in completely. All steps in the clinical laboratory investigations were standardized, and all were subject to ongoing reliability control. In the comparison of the analytical results for the alcoholics with reference intervals for healthy persons (normal ranges) the following alterations were found, the percentage of the alcoholics being given in parentheses. (Table: see text) Furthermore, the result was below the location parameter of the reference sample group for: Urea (80%) Thus excessive alcohol consumption is clearly a biological influence factor that must be taken into consideration in the medical assessment of analytical results for numerous clinical chemical and haematological parameters. In determining reference values and reference intervals for the transverse assessment of analytical results for these parameters it is therefore absolutely essential that subjects with excessive alcohol consumption be excluded from the reference sample group. According to the present data, alcoholism can be neither detected nor excluded by evaluating a single parameter, i.e. on the basis of only one clinical chemical finding.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0340-076X
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
65-77
pubmed:dateRevised
2007-7-24
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Excessive consumption of alcohol in men as a biological influence factor in clinical laboratory investigations.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't