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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1984-4-17
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pubmed:abstractText |
Plasmid analysis was used in the investigation of an outbreak of nosocomial Legionnaires' disease in four patients. Serogroup 1 strains were isolated from two patients, the air-conditioning cooling tower, and two hot-water tanks. All serogroup 1 strains contained two plasmids with approximate molecular masses of 21 and 48 megadaltons (Mdal). The serogroup 1 strain found in the cooling-tower isolate also contained an additional 1.9 Mdal-plasmid. Restriction-endonuclease analysis of the 21-Mdal plasmid that was present in patient and hot water-tank isolates revealed identical EcoRI and HaeIII fragment patterns. Digestion of the similarly sized plasmid in the cooling-tower isolate resulted in a unique fragment pattern. The data provide direct bacteriologic evidence implicating the hot-water tanks rather than the cooling tower as the source of the infecting strain.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0022-1899
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
149
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
251-6
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pubmed:dateRevised |
2006-5-1
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pubmed:meshHeading |
pubmed-meshheading:6699435-Cross Infection,
pubmed-meshheading:6699435-DNA, Bacterial,
pubmed-meshheading:6699435-Humans,
pubmed-meshheading:6699435-Legionella,
pubmed-meshheading:6699435-Legionnaires' Disease,
pubmed-meshheading:6699435-Plasmids,
pubmed-meshheading:6699435-Sputum,
pubmed-meshheading:6699435-Water Microbiology
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pubmed:year |
1984
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pubmed:articleTitle |
Plasmids as epidemiological markers in nosocomial Legionnaires' disease.
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pubmed:publicationType |
Journal Article
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