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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1984-3-15
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pubmed:abstractText |
Over a 3-year period, 149 Yucpa Indians in Venezuela developed hepatitis; 34 persons died and at least 22 developed chronic hepatitis. Children and young adults were primarily affected, especially males. Serologic testing showed that hepatitis B virus infection was highly endemic in this population, but also that 65% of patients had hepatitis B virus surface antigen (HBsAg) during or after illness. Most patients had evidence of delta-agent superinfection; 86% of HBsAg-positive patients had delta antibody, and delta antigen was found in specimens taken during autopsies on 7 of 9 patients. Serologic data suggested that most infections were due to delta superinfection of hepatitis B carriers, and that more than 60% of these infections progressed to chronic disease. Delta agent infection, and particularly delta superinfection of hepatitis B carriers, appears to be an ominous occurrence that may develop in populations among whom hepatitis B virus infection is endemic, and who have no other risk factor for delta infection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0003-4819
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
100
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
339-44
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6696355-Adolescent,
pubmed-meshheading:6696355-Adult,
pubmed-meshheading:6696355-Carrier State,
pubmed-meshheading:6696355-Child,
pubmed-meshheading:6696355-Child, Preschool,
pubmed-meshheading:6696355-Disease Outbreaks,
pubmed-meshheading:6696355-Female,
pubmed-meshheading:6696355-Hepatitis, Chronic,
pubmed-meshheading:6696355-Hepatitis, Viral, Human,
pubmed-meshheading:6696355-Hepatitis B,
pubmed-meshheading:6696355-Hepatitis B Surface Antigens,
pubmed-meshheading:6696355-Humans,
pubmed-meshheading:6696355-Indians, South American,
pubmed-meshheading:6696355-Infant,
pubmed-meshheading:6696355-Male,
pubmed-meshheading:6696355-Venezuela
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pubmed:year |
1984
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pubmed:articleTitle |
Delta virus infection and severe hepatitis. An epidemic in the Yucpa Indians of Venezuela.
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pubmed:publicationType |
Journal Article
|