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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1984-3-19
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pubmed:abstractText |
Repeated conjunctival provocation tests (CPT) were done in 20 children with rhino-conjunctivitis due to birch pollen allergy. Compared with the first open challenge, three successive blinded CPTs were reproducible within an allergen strength difference of one 10-potency in 92% of the tests. Based on the data, a power function was constructed, making it possible to determine the number of patients needed to discriminate CPT sensitivity of a given magnitude between two populations. During the study period specific serum-IgE increased in only three of 19 patients, indicating that stimulation of IgE antibody production is not a common consequence of repeated tests. We conclude that CPT is useful in clinical research. When indicated in clinical routine, CPT is a safe and easy test with good precision.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0105-4538
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
37-41
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6696209-Adolescent,
pubmed-meshheading:6696209-Allergens,
pubmed-meshheading:6696209-Child,
pubmed-meshheading:6696209-Conjunctival Diseases,
pubmed-meshheading:6696209-Female,
pubmed-meshheading:6696209-Humans,
pubmed-meshheading:6696209-Hypersensitivity,
pubmed-meshheading:6696209-Male,
pubmed-meshheading:6696209-Pollen
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pubmed:year |
1984
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pubmed:articleTitle |
The precision of the conjunctival provocation test.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|