Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-3-20
pubmed:abstractText
In an attempt to resolve the conflicts relevant to intravenous fat emulsion compatibility two amino acids, L-valine and L-histidine monohydrochloride monohydrate, were chosen as intravenous additives, and these substances were investigated as to whether they could induce significant changes in the physicochemical properties of an intravenous soybean oil emulsion. The stability of the fat emulsion was evaluated in terms of gross visual observation, particle size distribution, surface tension, pH, and the zeta potential. It was found that (a) no significant difference was produced on the particle size distribution up to 7 d after admixing, (b) the mean diameter of oil globules was approximately 0.21-0.24 micron, and (c) the fat emulsion was sufficiently stable, with a zeta potential ranging between -30 and -60 mV. The relationship of the isoelectric point (pI) of the amino acids and the pH of the buffer solutions was determined to be one of the most important factors in the stability of the fat emulsion.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0022-3549
pubmed:author
pubmed:issnType
Print
pubmed:volume
73
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
91-4
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Study of intravenous hyperalimentation: effect of selected amino acids on the stability of intravenous fat emulsions.
pubmed:publicationType
Journal Article