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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1 Pt 1
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pubmed:dateCreated |
1984-3-5
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pubmed:abstractText |
Twenty-eight of 62 children (45%) with a history of sting-induced anaphylaxis and initially positive skin tests to venom(s) developed negative venom skin tests to one or more of the venoms used in their treatment after 3 yr or more of immunotherapy. Children who developed negative venom skin tests were less sensitive prior to treatment, as judged by venom skin tests and venom-specific IgE antibody determinations, than children who maintained positive venom skin tests. Levels of venom-specific IgE antibodies declined with time in most children, but to lower levels in those with negative skin tests. Venom-specific IgG antibody levels were similar in both patients with negative skin tests and those with persistently positive skin tests. The development of negative skin tests may reflect a loss of allergic sensitivity, which is sufficient to allow the physician to consider the discontinuation of venom injections.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0091-6749
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
61-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6693669-Adolescent,
pubmed-meshheading:6693669-Antibody Specificity,
pubmed-meshheading:6693669-Bee Venoms,
pubmed-meshheading:6693669-Child,
pubmed-meshheading:6693669-Child, Preschool,
pubmed-meshheading:6693669-Humans,
pubmed-meshheading:6693669-Immunoglobulin G,
pubmed-meshheading:6693669-Immunotherapy,
pubmed-meshheading:6693669-Insect Bites and Stings,
pubmed-meshheading:6693669-Radioallergosorbent Test,
pubmed-meshheading:6693669-Skin Tests,
pubmed-meshheading:6693669-Time Factors
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pubmed:year |
1984
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pubmed:articleTitle |
The development of negative skin tests in children treated with venom immunotherapy.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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