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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1984-3-8
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pubmed:abstractText |
The etiology of avian muscular dystrophy was examined by a cross-transplantation technique. Care was taken for the transplants to regenerate and develop under neural influence, by using the small extensor carpi radialis longus (ECRL) muscle. The ECRL muscles were exchanged between normal and dystrophic chicks 2 to 3 days ex ovo, and the muscle weight, number of muscle fibers, muscle fiber size, and contractile properties of the transplanted muscles were observed 60 to 65 days after operation when the tissue reconstitution was virtually complete. The results obtained for the physiologic, anatomic, and histologic parameters strongly suggested that there exists some failure in the host environment of the dystrophic chicken. The analyses of the histologic parameters suggested that a genetic disorder may also reside in the muscle tissue itself. The myotonic nature of the muscle membrane, however, probably does not contribute significantly to the abnormal behavior of dystrophic chickens. The importance of some neurogenic abnormalities in avian muscular dystrophy is discussed in relation to the results reported by other investigators.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0014-4886
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
83
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
392-402
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6692875-Action Potentials,
pubmed-meshheading:6692875-Animals,
pubmed-meshheading:6692875-Animals, Newborn,
pubmed-meshheading:6692875-Chickens,
pubmed-meshheading:6692875-Leg,
pubmed-meshheading:6692875-Muscle Contraction,
pubmed-meshheading:6692875-Muscle Development,
pubmed-meshheading:6692875-Muscles,
pubmed-meshheading:6692875-Muscular Dystrophies,
pubmed-meshheading:6692875-Organ Size,
pubmed-meshheading:6692875-Regeneration
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pubmed:year |
1984
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pubmed:articleTitle |
Transplantation of extensor carpi radialis longus muscle in normal and dystrophic chicks.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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