Linked Life Data

6689877

Source:http://linkedlifedata.com/resource/pubmed/id/6689877

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-1-26
pubmed:abstractText
The nonspecific host defense system of 66 patients with thermal injuries was studied prospectively. Our goal was to correlate the magnitude of injury with changes in host defenses and to determine if the responses of patients with and without sepsis were different. Eighteen patients experienced one or more septic episodes. Synchronous serial measurements of circulating fibronectin levels, neutrophil locomotive activity and phagocytosis, and intracellular killing in all patients showed that multiple components of the nonspecific host defense system were impaired after thermal injury. The depression of random migration and chemotaxis and the magnitude of the initial depression in serum fibronectin levels were related to the severity of injury but did not predict sepsis. Only a decrease in neutrophil bactericidal activity or a secondary depression in the serum fibronectin level was associated with the onset of sepsis.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0004-0010
pubmed:author
pubmed:issnType
Print
pubmed:volume
119
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
83-9
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Sequential prospective analysis of the nonspecific host defense system after thermal injury.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.